DavidsonX: Measuring Pharmacodynamics: From Ligand Binding to Clinical Outcomes
Last updated on June 2, 2025 5:08 pm
Drugs are biologically active compounds. Drug discovery and drug development rely on methods for measuring biological activity. The term “activity” is quite general. In practice, a substance’s biological activity can refer to how a substance affects a biological pathway, cell-level responses, safety risks, how long a substance resides within in a system, as well as a substance’s effects in an organism (called pharmacodynamics). The design of methods for measuring activity is a critical aspect of drug discovery. The design of robust and informative methods can accelerate the drug discovery and development process.
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