Drug Delivery: Principles and Engineering

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This course introduces concepts of drug delivery to meet medical challenges. The course is designed to be modular, with each module focusing on the various aspects of drug delivery.

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COURSE LAYOUT

Week 1 : Pharmacokinetics: Bioavailability, Elimination, Therapeutic index
Week 2 : Prodrugs, Controlled release
Week 3 : Polymers: Synthesis, properties, characterization, crystallinity and amorphousness
Week 4 : Biopolymers: Natural and Synthetic, biocompatibility, Biodegradation, commonly used biopolymers
Week 5 : Polymer-Drug conjugates, PEGylation
Week 6 : Diffusion controlled systems, Ficks laws, Reservoir systems, Non-erodible matrix systems, Bio-erodible Systems
Week 7 : Hydrogels: Physical or chemical, pore-size calculation, in-situ crosslinking
Week 8 : Nano and Micro-particles: Dendrimers, Liposomes, Micelles
Week 9 : Metal and polymeric particles, effect of particle shape, charge and elasticity
Week 10: Protein Adsorption and tissue engineering, Drug delivery in tissue engineering
Week 11: Implant associated infections, Route specific delivery: Oral, Subcutaneous, Intramuscular, transdermal, inhalation, intravenous
Week 12: Vaccines, Cancer vaccines, Cell and gene delivery, Smart responsive drug delivery, Targeted drug delivery, Nanotoxicology and market translation.

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    Drug Delivery: Principles and Engineering
    Drug Delivery: Principles and Engineering

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