Updated Comprehensive Guide to Bioinformatics Databases
Learn about bioinformatics databases and their importance in biological data analysis. Gain knowledge on UCSC Genome Browser and sequence analysis tools. Perfect for data scientists and researchers.
What you’ll learn
- You will gain complete understanding on Bioinformatics Databases. From basic to advance concepts.
- After this practical course you will confidently choose database according to your research need without any doubts.
- Different databases used in bioinformatics
- They will be able to use and know different categories of sub-databases of NCBI.
- Plant and Genome Databases
- Primary Databases in Bioinformatics
- Secondary Databases in Bioinformatics
- After this course Students will have intermediate Knowledge of UCSC Genome Browser in Bioinformatics.
- Students will be able to use different tools for Sequence Analysis and will know different categories of sub-databases.
- Students will be able to use different tools of UCSC for Genome Analysis.
- Students will be Able to perform Genome analysis on any gene
- Tools Used in Plant Databases
- They will be able to use and know different categories of sub-databases of Plant Databases.
- Top ten databases being used in plant bioinformatics
- Different Plant databases used in bioinformatics
- Complete up-to Date Beginner’s Guide of top Plant Databases Used in Bioinformatics along with their utilization
- You will gain concrete diffrences between Primary, Seconday and Composite database. The knowledge will help you to choose curated and reviewed data.
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What is bioinformatics?
In biology, bioinformatics is defined as, “the use of a computer to store, retrieve, analyze or predict the composition or structure of bio-molecules”. Bioinformatics is the application of computational techniques and information technology to the organization and management of biological data. Classical bioinformatics deals primarily with sequence analysis.
Aims of bioinformatics
Development of a database containing all biological information.
Development of better tools for data designing, annotation, and mining.
Design and development of drugs by using simulation software.
Design and development of software tools for protein structure prediction function, annotation, and docking analysis.
Creation and development of software to improve tools for analyzing sequences for their function and similarity with other sequences
Biological databases
Biological data are complex, exception-ridden, vast, and incomplete. Therefore several databases have been created and interpreted to ensure unambiguous results. A collection of biological data arranged in a computer-readable form that enhances the speed of search and retrieval and is convenient to use is called a biological database. A good database must have updated information.
Importance of biological database
A range of information like biological sequences, structures, binding sites, metabolic interactions, molecular action, functional relationships, protein families, motifs, and homologous can be retrieved by using biological databases. The main purpose of a biological database is to store and manage biological data and information in computer-readable forms.
In this course, we learned about the different biological databases that are being used in bioinformatics and get to know a little bit about their details. Mainly these databases are divided into four categories and we learned about base by base. And explained the difference between the primary and secondary databases and explained their utilization in bioinformatics.
This course will be extremely helpful to students of data analysts and bioinformaticians because they use the databases a lot in their work.
If you guys have any questions or suggestions please let me know in the instructor’s inbox I’ll try to answer all of your questions within 12 hours.
Genome Browser
This course is mainly about the primary database browser called UCSC. The University of California Santa Cruz (UCSC) Genome Browser is a popular Web-based tool for quickly displaying a requested portion of a genome at any scale, accompanied by a series of aligned annotation “tracks.” The annotations generated by the UCSC Genome Bioinformatics Group and external collaborators include genes.
It is an interactive website offering access to genome sequence data from a variety of vertebrate and invertebrate species and major model organisms, integrated with a large collection of aligned annotations. The Browser is a graphical viewer optimized to support fast interactive performance and is an open-source, web-based tool suite built on top of a MySQL database for rapid visualization, examination, and querying of the data at many levels. The Genome Browser Database, browsing tools, downloadable data files, and documentation can all be found on the UCSC Genome Bioinformatics website.
In this course, we will be mainly covering the utilization of the UCSC Genome Browser and performing the whole scenario on SARS-COV-2(a strain of coronavirus).
And mainly learning about the Table Browser. Table Browser is also used to calculate intersections between tracks, and to retrieve DNA sequences covered by a track.
All these videos will be divided into three parts containing the Introduction, Explanation, and Summary so All of you can easily understand the Course.
Who this course is for:
- Data Scientist are Encouraged to take this course
- Researchers are also encouraged to take this Course
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