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Virology provides information on viruses, which are associated with several emerging infectious diseases in both animals and plants. Most of the viral diseases are not curable and developing treatment strategy for these diseases is the real tough challenge for the researchers. It is possible only when all the information on its structure, replication, mode of transmission and especially methods of cultivating viruses are easily available. This will pay the way for understanding pathogenicity and targets for drug development. Prevention is better than cure suits better with the viral infections. Hence this course is developed to provide knowledge on nature, host and replication of different group of viruses, spread and management of viral diseases. The course also provides information on beneficial aspects of virus, especially its use in medicine and agriculture. The syllabus is designed keeping in mind the recent developments in virology and will be useful to all those who want to learn and update their knowledge on viruses.

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COURSE LAYOUT

First Week
Day 1
Discovery, nature, origin and evolutionary importance of viruses
First Week
Day 2
Structure of Viruses
First Week
Day 3
Isolation, purification and cultivation of viruses
First Week
Day 4
Viral taxonomy: Classification and nomenclature of different groups of viruses
First Week
Day 5
? MCQ ? Assignments

Second Week
Day 1
Diversity, classification and one step multiplication curve

Second Week
Day 2
Lytic and lysogenic phages

Second Week
Day 3
Regulation of transcription in lambda phage

Second Week
Day 4
Phage phenotypes, phenotype mixing and phage therapy

Second Week
Day 5
? MCQ ? Assignments

Third Week
Day 1
Principal events involved in replication: Adsorption, penetration and uncoating.

Third Week
Day 2
Viral nucleic acid and protein synthesis

Third Week
Day 3
Intracellular trafficking, assembly, maturation and release

Third Week
Day 4
Host response to viral infection

Third Week
Day 5
? MCQ ? Assignments

Fourth Week
Day 1
TMV and BBTV

Fourth Week
Day 2
Herpes, Polio and Influenza virus

Fourth Week
Day 3
SV40 and Adeno Virus, Poxviruses

Fourth Week
Day 4
Hepatitis and Retroviruses

Fourth Week
Day 5
? MCQ ? Assignments
Fifth Week
Day 1
Visualization and enumeration of virus particles
Fifth Week
Day 2
Physical and biological methods of detection of viruses
Fifth Week
Day 3
Immunological and molecular methods detection of viruses
Fifth Week
Day 4
Characterization of viral product expressed in the infected cells
Fifth Week
Day 5
? MCQ ? Assignments
Sixth Week
Day 1
General methods of propagation of plant viruses
Sixth Week
Day 2
Purification of plant viruses using centrifugation, chromatography and electrophoresis techniques
Sixth Week
Day 3
Methods employed in identification of plant viruses
Sixth Week
Day 4
Viruses as biopesticides
Sixth Week
Day 5
? MCQ ? Assignments

Seventh Week
Day 1
Common cold, SARS, Influenza

Seventh Week
Day 2
Measles, Mumps, Rubella, Human papilloma

Seventh Week
Day 3
Herpes, Polio, Rabies, Small pox

Seventh Week
Day 4
HIV, Hepatitis, Dengue, Yellow fever

Seventh Week
Day 5
? Quizzes ? Assignments ? Paragraph and essay questions

Eighth Week
Day 1
Introduction to oncogenic viruses

Eighth Week
Day 2
Concepts of oncogenes and proto-oncogenes

Eighth Week
Day 3
Understanding human carcinogenesis by using tumor viruses as experimental tools

Eighth Week
Day 4
Prevention and treatment of virus induced cancer

Eighth Week
Day 5
? MCQ ? Assignments

Ninth Week
Day 1
Host specific and nonspecific defense mechanisms involved in resistance to and recovery from virus infections

Ninth Week
Day 2
Role of interferon in viral infections

Ninth Week
Day 3
Viral Chemotherapy: Nucleoside analogs, reverse transcriptase inhibitors, protease inhibitors

Ninth Week
Day 4
History of vaccines especially smallpox and polio. New methods: subunit vaccines, anti-idiotype and DNA vaccines

Ninth Week
Day 5
? MCQ ? Assignments
Tenth Week
Day 1
Use of viral vectors in cloning and expression
Tenth Week
Day 2
Gene therapy and Phage display
Tenth Week
Day 3
Emerging and re emerging viruses
Tenth Week
Day 4
Viruses and future
Tenth Week
Day 5
? MCQ ? Assignments

Eleventh Week
Day 1
Exam preparation and assessment of assignments

Eleventh Week
Day 2
Exam preparation and assessment of assignments

Eleventh Week
Day 3
Exam preparation and assessment of assignments

Eleventh Week
Day 4
Exam preparation and assessment of assignments

Eleventh Week
Day 5
Exam preparation and assessment of assignments
Twelfth Week
Day 1
Assessment at the end of the course, which comprises of 40% of Online or In-term assessment and 60% Proctored end term exam.
Twelfth Week
Day 2
Assessment at the end of the course, which comprises of 40% of Online or In-term assessment and 60% Proctored end term exam.
Twelfth Week
Day 3
Assessment at the end of the course, which comprises of 40% of Online or In-term assessment and 60% Proctored end term exam.
Twelfth Week
Day 4
Assessment at the end of the course, which comprises of 40% of Online or In-term assessment and 60% Proctored end term exam.
Twelfth Week
Day 5
Assessment at the end of the course, which comprises of 40% of Online or In-term assessment and 60% Proctored end term exam.

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